study of regulatory promoter polymorphism (-248 g>a) of bax gene in patients with gastric cancer in the northern provinces of iran

نویسندگان

seyedeh habibeh mirmajidi

mojtaba najafi

seyedeh tahereh mirmajidi

nafiseh nasri nasrabadi

چکیده

aim : the aim of this study is to evaluate the polymorphism in bax gene and its association with some clinical pathology traits in gastric cancer.   background : gastric cancer is considered as the fourth most common cancer in the north and northwest of iran. bcl2 family has a key role in regulation of apoptosis, and any changes in the expression of bcl2 lead to cancer. patients and methods : blood samples were collected from 100 cases and 89 controls in the northern provinces of iran to evaluate promoter polymorphism (-248g

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15 صفحه اول

Study of regulatory promoter polymorphism (-248 G>A) of Bax gene in patients with gastric cancer in the northern provinces of Iran

AIM The aim of this study is to evaluate the polymorphism in Bax gene and its association with some clinical pathology traits in gastric cancer. BACKGROUND Gastric cancer is considered as the fourth most common cancer in the north and northwest of Iran. Bcl2 family has a key role in regulation of apoptosis, and any changes in the expression of Bcl2 lead to cancer. PATIENTS AND METHODS Blood...

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عنوان ژورنال:
gastroenterology and hepatology from bed to bench

جلد ۱، شماره ۹، صفحات ۲۰۱۶-۹

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